© 2019 NBMrg Brazil

Research

 

The NBMrg applies nanotechnology in the most diverse areas

GNPs Interaction with the heart physiology

 

Currently the Gold Nanoparticles (GNPs) have great potential for biomedical applications, due to the fact that they have antioxidant and anti-inflammatory effects. These effects can be further enhanced by functionalization with Glutathione, an endogenous antioxidant. However, the interaction of this nanomaterial with cardiac tissue is still little explored. 

Carbon Nanotubes

Applications:

Cancer Treatment

Diagnosis of infectious diseases

Ceramics Odondológicas

Gold Nanoparticles

 

Applications:

Cancer Treatment

Diagnosis of infectious diseases

Interaction with cardiac physiology

Measurement properties associated with different types of proteins

 
Nanocomplex based on bioconjugate-cetuximab gold nanoparticles

 

Cetuximab is an efficient immunotherapy agent to treat epithelial cancers. However, resistance and severe side-effects have been reported. Due to the physical-chemical properties of gold nanoparticles, in special the possibility of biomolecules conjugation on their surfaces, studies using nanocomplex based on bioconjugate-cetuximab gold nanoparticles are in progress to optimize cetuximab effects as well as decreasing its side-effects. Besides, characterization, biological effects on human cancer cells and follow up of nanocomplex stability is already in course.